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James A Shayman Selected Research

3',4'- ethylenedioxyphenyl- 2- palmitoylamino- 3- pyrrolidino- 1- propanol

7/2012Globoside promotes activation of ERK by interaction with the epidermal growth factor receptor.

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James A Shayman Research Topics

Disease

17Fabry Disease (Fabry's Disease)
01/2019 - 02/2003
9Gaucher Disease (Gaucher's Disease)
10/2020 - 07/2007
5Insulin Resistance
12/2016 - 07/2009
5Atherosclerosis
03/2015 - 02/2005
4Lysosomal Storage Diseases (Lysosomal Storage Disease)
12/2018 - 07/2007
4Inflammation (Inflammations)
01/2017 - 01/2010
4Stroke (Strokes)
09/2009 - 02/2003
3Polycystic Kidney Diseases (Polycystic Kidney Disease)
01/2016 - 07/2010
3Thrombosis (Thrombus)
07/2014 - 04/2006
3Myocardial Infarction
07/2007 - 02/2003
2Kidney Diseases (Kidney Disease)
01/2018 - 01/2016
2Diabetic Nephropathies (Diabetic Nephropathy)
01/2016 - 08/2015
2Infections
08/2014 - 05/2009
2Obesity
01/2014 - 06/2010
2Type 2 Diabetes Mellitus (MODY)
11/2013 - 01/2013
2Neoplasms (Cancer)
11/2013 - 07/2012
2Splenomegaly
01/2013 - 08/2006
1Inborn Genetic Diseases (Disease, Hereditary)
12/2017
1Uveitis
01/2017
1Renal Cell Carcinoma (Grawitz Tumor)
01/2016
1Hypertrophy
08/2015
1Fibrosis (Cirrhosis)
08/2015
1Hyperglycemia
08/2015
1Chronic Renal Insufficiency
04/2015
1Lecithin Cholesterol Acyltransferase Deficiency (Lecithin:Cholesterol Acyltransferase Deficiency)
03/2015
1Acute Coronary Syndrome
03/2015
1Autosomal Dominant Polycystic Kidney (ADPKD)
11/2013
1Sandhoff Disease (Sandhoff's Disease)
04/2013
1Neurodegenerative Diseases (Neurodegenerative Disease)
04/2013
1Niemann-Pick Diseases (Niemann Pick Disease)
03/2013
1Hepatomegaly
01/2013
1Thrombocytopenia (Thrombopenia)
01/2013
1Anemia
01/2013
1Wounds and Injuries (Trauma)
07/2012
1Drug-Related Side Effects and Adverse Reactions
01/2011
1Heart Diseases (Heart Disease)
09/2009
1Body Weight (Weight, Body)
07/2009

Drug/Important Bio-Agent (IBA)

16GlycosphingolipidsIBA
01/2019 - 02/2003
10alpha-Galactosidase (Beano)IBA
09/2009 - 02/2003
8eliglustatIBA
10/2020 - 07/2007
7GalactosidasesIBA
01/2019 - 11/2010
6Glucosylceramides (Glucocerebrosides)IBA
10/2020 - 07/2007
6ceramide glucosyltransferaseIBA
10/2020 - 07/2007
6globotriaosylceramide (globotriosylceramide)IBA
07/2014 - 11/2008
4HydrolasesIBA
01/2019 - 11/2010
4EnzymesIBA
01/2019 - 06/2010
3CeramidesIBA
12/2016 - 08/2008
3SphingolipidsIBA
12/2016 - 08/2008
3Pharmaceutical PreparationsIBA
12/2015 - 07/2009
3Glucose (Dextrose)FDA LinkGeneric
08/2015 - 07/2009
3Phospholipids (Phosphatides)FDA LinkGeneric
03/2013 - 08/2006
2Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
12/2018 - 01/2014
2Phospholipases A2 (Phospholipase A2)IBA
01/2017 - 08/2006
23-nitrotyrosineIBA
07/2014 - 02/2005
2Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2014 - 09/2009
2GangliosidesIBA
04/2013 - 05/2009
2imigluceraseFDA Link
01/2013 - 06/2010
2GlycolipidsIBA
09/2009 - 05/2009
2ApolipoproteinsIBA
08/2008 - 02/2005
2LipidsIBA
07/2007 - 08/2006
2Neutral GlycosphingolipidsIBA
02/2005 - 02/2003
1venglustatIBA
10/2020
1sphingosyl beta-glucosideIBA
10/2020
1von Willebrand FactorIBA
01/2019
1Small Interfering RNA (siRNA)IBA
12/2018
1Apolipoprotein A-I (Apolipoprotein A1)IBA
12/2017
1Phospholipases (Phospholipase)IBA
01/2017
1Travoprost (Travatan)FDA Link
01/2017
1Glial Fibrillary Acidic ProteinIBA
01/2017
1Timolol (Blocadren)FDA LinkGeneric
01/2017
1EndotoxinsIBA
01/2017
1Antiglaucoma AgentsIBA
01/2017
1LipopolysaccharidesIBA
01/2017
1dorzolamide (Trusopt)FDA LinkGeneric
01/2017
1Extracellular Matrix ProteinsIBA
08/2015
1TensinsIBA
08/2015
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
08/2015
1AerosolsIBA
08/2014
1Biomarkers (Surrogate Marker)IBA
07/2014
1Oxidants (Oxidizing Agents)IBA
07/2014
1Reactive Nitrogen SpeciesIBA
01/2014
1OxalatesIBA
04/2013
1Hexosaminidases (Hexosaminidase)IBA
04/2013
1tyrosine receptor (receptor, tyrosine)IBA
01/2013
1Phosphotransferases (Kinase)IBA
01/2013
13',4'- ethylenedioxyphenyl- 2- palmitoylamino- 3- pyrrolidino- 1- propanolIBA
07/2012
1Stage-Specific Embryonic AntigensIBA
07/2012
1Insulin (Novolin)FDA Link
06/2010
1Glucosylceramidase (Glucocerebrosidase)IBA
06/2010
1miglustat (Zavesca)FDA Link
06/2010
1GlucocorticoidsIBA
05/2010
1Biological ProductsIBA
01/2010
1DNA (Deoxyribonucleic Acid)IBA
01/2010
1Hemoglobins (Hemoglobin)IBA
07/2009
1Triglycerides (Triacylglycerol)IBA
07/2009

Therapy/Procedure

8Therapeutics
10/2020 - 02/2003
3Enzyme Replacement Therapy
11/2013 - 06/2010
2Enzyme Therapy
11/2010 - 07/2007
1Topical Administration
01/2017
1Intravenous Administration
06/2010